Two sample MR report
NUDT14_Endothelial Cell (Endo) against bbj-a-88
Date: 13 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.1841958 | 0.7583994 | 0.8483183 |
| Weighted median | 3 | -0.0581923 | 0.0226770 | 0.0102839 |
| Inverse variance weighted | 3 | -0.0613288 | 0.0165900 | 0.0002184 |
| Simple mode | 3 | -0.0575251 | 0.0244526 | 0.1429422 |
| Weighted mode | 3 | -0.0575251 | 0.0250007 | 0.1480526 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0179594 | 1 | 0.8933924 |
| Inverse variance weighted | 0.1228175 | 2 | 0.9404387 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.138917 | 0.4289972 | 0.8006346 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.41e-05 | 0 | TRUE | 0.5324527 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
